A SYSTEM FOR COMPUTATIONAL ANALYSIS AND RECONSTRUCTION OF 3D COMMINUTED BONE FRACTURES

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Liu, P. (2012). A SYSTEM FOR COMPUTATIONAL ANALYSIS AND RECONSTRUCTION OF 3D COMMINUTED BONE FRACTURES. Unc Charlotte Electronic Theses And Dissertations.
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Abstract

High energy impacts at joint locations often generate highly fragmented, or comminuted bone fractures. A leading current approach for treatment requires physicians qualitatively to classify the fracture to one of four possible fracture severity cases. Each case then has a sequence of best-practices for obtaining the best possible prognosis for the patient. It has been observed that qualitative evaluation of fracture severity by physicians can vary significantlywhich can lead to potential misclassication and mis-treatment of these fracture cases. Major indicators of fracture severity are (i) fracture surface area, i.e., how much surface area was generated when the bone broke apart and (ii) dispersion, i.e., how far the fragments have rotated and translated from their original anatomic positions. Work in this dissertation develops computational tools that solve the bone puzzle-solving problem automatically or semi-automatically and extract previously unavailable quantitative information for these indicators from each bone fragment that are intended to assist physicians in making a more accurate and reliable fracture severity classification. The system applies novel three-dimensional (3D) puzzle-solving algorithms to identify the fracture fragments in the CT image data and piece them back together in a virtual environment. Doing so provides quantitative values for both fracture surface area and dispersion that reduce variability in fracture severity classifications and prevent mis-diagnosis for fracture cases that may be difficult to qualitatively classify using traditional approaches. This dissertation describes the system, the underlying algorithms and demonstrates the virtual reconstruction results and quantitative analysis of comminuted bone fractures from six clinical cases.

Details
Author

Liu, Pengcheng

Title

A SYSTEM FOR COMPUTATIONAL ANALYSIS AND RECONSTRUCTION OF 3D COMMINUTED BONE FRACTURES

Physical Description

1 online resource (155 pages) : PDF

Date

2012

Degree Granting Institution

University of North Carolina at Charlotte

Abstract

High energy impacts at joint locations often generate highly fragmented, or comminuted bone fractures. A leading current approach for treatment requires physicians qualitatively to classify the fracture to one of four possible fracture severity cases. Each case then has a sequence of best-practices for obtaining the best possible prognosis for the patient. It has been observed that qualitative evaluation of fracture severity by physicians can vary significantlywhich can lead to potential misclassication and mis-treatment of these fracture cases. Major indicators of fracture severity are (i) fracture surface area, i.e., how much surface area was generated when the bone broke apart and (ii) dispersion, i.e., how far the fragments have rotated and translated from their original anatomic positions. Work in this dissertation develops computational tools that solve the bone puzzle-solving problem automatically or semi-automatically and extract previously unavailable quantitative information for these indicators from each bone fragment that are intended to assist physicians in making a more accurate and reliable fracture severity classification. The system applies novel three-dimensional (3D) puzzle-solving algorithms to identify the fracture fragments in the CT image data and piece them back together in a virtual environment. Doing so provides quantitative values for both fracture surface area and dispersion that reduce variability in fracture severity classifications and prevent mis-diagnosis for fracture cases that may be difficult to qualitatively classify using traditional approaches. This dissertation describes the system, the underlying algorithms and demonstrates the virtual reconstruction results and quantitative analysis of comminuted bone fractures from six clinical cases.

Genre

doctoral dissertations

Subjects--Topics

Electrical engineering
Computer science

Degree

Ph.D.

Keywords

3D Reconstruction
Automatic
Fracture Severity
System

Subject Area

Electrical Engineering

Advisor(s)

Willis, Andrew

Committee Members

Weldon, Thomas
Xie, Jiang
Wilkinson, Anthony
Souvenir, Richard

Degree Note

Thesis (Ph.D.)--University of North Carolina at Charlotte, 2012.

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Rights Holder Information

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Identifier

Liu_uncc_0694D_10395

Permalink

http://hdl.handle.net/20.500.13093/etd:1614