Opportunities to discuss options for care when faced with a life limiting disease is the right of all patients. Yet, healthcare provider feelings of awkwardness, fear of diminishing hope, and fear of failing to cure can result in missed opportunit...
Ovarian cancer is the most lethal gynecologic cancer in the United States. If caught in early stages, patient survival rate is 94%, late stage survival rates drop to 28%. It is because most cases are caught in late stages that high mortality is se...
Nanoparticles are an innovative platform for cancer treatment that reduces systemic toxicity and allows for active targeting of tumor sites to enhance the therapeutic efficacy. Mesoporous silica nanoparticles (MSNs) have emerged as an attractive d...
ABSTRACTAMY B. EDINGER. How Do the Homeless Newly Diagnosed with Cancer Receive Safe and Cost-Effective Healthcare During Year One Following Diagnosis? (Under the direction of DR. STEPHANIE WOODS) Cancer is one of the most common causes of mortali...
In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...
This thesis is a comparative review of skeletal elements from coastal and highland regions of Peru to determine if altitude effects the incidence of skeletal cancer formations. Pathological analysis was completed on 372 skeletal elements: 299 elem...
ABSTRACTSARA SHAHBAZI. Patient and Provider Level Predictors of Breast Surgeons’ Practice Styles and Modality Approaches for Mastectomy Procedures(Under the direction of DR. LARISSA R. BRUNNER HUBER)Background: Breast cancer surgery, including mas...
Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...
Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...
Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus. Lack of preexisting immunity against VSV, inherent oncotropism, and genetic malleability make VSV a widely used platform for vaccine, oncolytic, and gene ther...