Search results
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Title
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Ajuga turkestanica increases Notch and Wnt signaling in aged skeletal muscle
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Author
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Arthur, Susan, Howden, Reuben, Zwetsloot, Kevin, Shanely, Andrew
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Subjects--Topical
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Musculoskeletal system, Cells
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Description
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Abstract. – BACKGROUND: The declining myogenic potential of aged skeletal muscle is multifactorial. Insufficient satellite cell activity is one factor in this process. Notch andWnt signaling are involved in various biological processes including o...
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Title
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GSI treatment preserves protein synthesis in C2C12 myotubes
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Author
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Arthur, Susan, Huot, Joshua, Marino, Joseph S., Thompson, Brian, McMullen, Charlotte
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Subjects--Topical
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Muscle proteins, Cells
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Description
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It has been demonstrated that inhibiting Notch signaling through γ-secretase inhibitor (GSI) treatment increases myogenesis, AKT/mTOR signaling, and muscle protein synthesis (MPS) in C2C12 myotubes. The purpose of this study was to determine if GS...
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Title
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New perspectives on SNARE function in the yeast minimal endomembrane system
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Author
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Chi, Richard J., Grissom, James H., Segarra, Veronica A.
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Subjects--Topical
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Endocytosis, Cells
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Description
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Saccharomyces cerevisiae is one of the best model organisms for the study of endocytic membrane trafficking. While studies in mammalian cells have characterized the temporal and morphological features of the endocytic pathway, studies in budding y...