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Influence of Notch Inhibition on Mtor and Wnt Signaling in Reparing Muscle
Title
Influence of Notch Inhibition on Mtor and Wnt Signaling in Reparing Muscle
Author
Williams III, James
Date Created
2023
Subjects--Topical
Kinesiology
Description
Protein synthesis and muscle stem cells are crucial components of adequate muscle repair in healthy individuals that are dysregulated in a variety of diseases states. A key regulator of muscle stem cell activation and coordination of downstream mu...
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Title
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Author
Huot, Joshua
Date Created
2018
Subjects--Topical
Molecular biology, Kinesiology
Description
Aging can be accompanied by aggressive loss of muscle mass (sarcopenia) and is a primary prognosticator for the reduced capacity of the elderly to accomplish basic activities of daily living. Several mechanisms within skeletal muscle lead to devel...